We are seeking a Research Associate II to perform routine testing and data analysis as a member of the Analytical Sciences team. Reporting to a Staff Scientist, this position contributes to Analytical Science’s molecular, cell and virus biology, enzyme and protein, biophysics and structural biology, and analytical chemistry sub teams. You will have the opportunity to make a lasting impact as you partner with Process Development and GMP Manufacturing in order to support release of clinical material for all drug modalities (in vivo and ex vivo therapies) This role will be based in Emeryville, California.
How you’ll contribute:
- Execute routine testing on multiple assays to support potency, impurity, identity and other characterization testing
- Follow SOPs or work instructions during assay execution, author summary reports
- Maintain accurate and complete documentation of any scientific experimental plan, data and report; operate under Good Documentation Practice for efficient data management and retrieval
- Ensure that all work follows the required regulatory standards, conforms to company policies and standard operating procedures (SOPs)
- Follow Environment, Health & Safety policies, ensure safe environmental and working conditions in the lab
- Work on multiple projects to meet departmental and organization goals
- Troubleshoot instruments and methods
- Contribute to laboratory maintenance
What you bring:
- BSc/MSc degree in Molecular and cell biology, Virology, Biochemistry, Biophysics, Material science, Analytical chemistry, Organic chemistry or other closely related life sciences discipline, with at least 0-2+ years (for BSc/MSc) of relevant experience along in an analytical development lab and/or a QC analytical laboratory
- Understanding and hands-on experience of several of the following assays: protein/enzyme assays (ELISA, SDS-PAGE, kinetics etc.), biophysical assays (enzyme activity, particle analysis and characterization (DLS, MALS, zeta potential), HPLC-SEC, RP-HPLC, mass spectrometry, SoloVPE), and small molecule, lipid and RNA/oligonucleotide assays (e.g., CE, IP-RP-HPLC, affinity chromatography, residual solvent and small molecule impurities etc.), and molecular, virus and cell-based assays (e.g., ddPCR, qPCR, TCID50, rcAAV, cell bank testings etc.)
- Experience with CRISPR/Cas, mRNA/LNP, viral vectors, gene and cell therapy, CAR-T, and iPSC technology is an advantage
- Experience with electronic systems such as ELN, LIMS, Trackwise, Veeva, etc., is an advantage
- Flexible to meet changing demands to support process development and manufacturing activities
- Ability to prioritize project work with multiple tasks/deadlines, and make effective use of available resource to meet agreed timelines
- Ability to problem solve and identify root cause
- Ability to effectively communicate several levels up and across various functions
- Strong interpersonal and communications skills; h ighly collaborative, team-oriented, thrives in a fast-moving, results-oriented startup environment with urgent deadlines
- Independent and self-sufficient, self-motivated
California Pay Transparency Disclosure:
This position is classified as an exempt position under the Federal Labor Standards Act. The anticipated base salary range for this position will be $82,000 - $95,000 . You will also be eligible to receive equity, bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on location, skill level, years and depth of relevant experience, and education.
About Metagenomi
Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world. For more information, please visit https://metagenomi.co/.
What makes Metagenomi a unique place to work?
- We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating disease.
- We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more!
- We offer competitive compensation including a market-benchmarked salary, annual target bonus, equity in an early-stage startup, and a comprehensive benefits plan, including 401(k) matching, a retirement safe harbor plan, and other perks.
At Metagenomi, we know that our people drive our success. We are an equal-opportunity employer and believe in and value diversity and inclusion. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. Metagenomi does not discriminate on the basis of race, color, religion, sexual orientation, gender, age, physical or mental disability, or any other status protected under federal, state, or local law. Please note, all candidates must be authorized to work in the United States.
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Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi’s Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.