Metagenomi is a biotechnology company headquartered in Emeryville, CA developing next-generation human therapeutics using gene-editing systems derived from environmental microbes. We are seeking a motivated individual for a Director-level position that will lead a group focusing on the understanding, engineering, production, and delivery of RNA-based gene-editing reagents. Candidates should be enthusiastic, passionate, have attention to detail, and a desire to change the world. This role will be based in Emeryville, CA .
About the Role
The day-to-day responsibilities of this role will include:
- Lead, mentor, and expand a research team focused on applied RNA biology
Design and optimize gene-editing tool mRNAs
Design and optimize gene-editing tool guide RNAs
Lead/participate in a cross-functional group focused on mRNA/guide RNA lipid nanoparticle delivery
Improve the overall potency of Metagenomi’s gene-editing reagents
Collaborate with the Discovery team to extend RNA engineering solutions to new editing tools
Collaborate with others in the Genome Editing group to understand the specificity of engineered tools
Be a source of technical advice and support for our Scientists and Research Associates across the company
Gather and analyze experimental data, present to key stakeholders
Prepare accurate and timely data summaries and contribute to writing of reports, papers, and patent manuscripts
Keep up-to-date on the competitive landscape of technological advances and, where appropriate, propose new areas of research that will advance the company’s technology platform
Present at external scientific meetings
Other duties as assigned
The anticipated base salary range for this position will be $180,000 - $205,000 depending on the exact level of the role.As this role is open to candidates with a wide range of skills and experience, the exact salary will be dependent on the specific level of the position. We value transparency and will make every effort to provide you with a succinct explanation for how the final salary within this range is determined.
Desired Qualifications
PhD in biology, chemistry, or a related discipline and 7+ years of relevant research experience
Experience leading and growing research teams consisting of both BS- and PhD-level members
Track record of successful RNA engineering and/or LNP-based delivery methods
Technical expertise surrounding nucleic acid chemistry and LNP delivery
Expertise (5+ years) with mammalian cell culture
Facility with high-throughput DNA sequencing-based assays
Excellent organizational skills and both oral and written communication skills
Ability to think strategically, manage time and workflow, and work independently as well as in a results-oriented research team
Preferred Qualifications
10+ years of research experience in industry
Track record of successful RNA engineering and LNP-based delivery methods
Experience with genome editing technologies
Please note, all candidates must be authorized to work in the United States.
About Metagenomi
Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world. For more information, please visit https://metagenomi.co/.
What makes Metagenomi a unique place to work?
- We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating disease.
- We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more!
- We offer competitive compensation including a market-benchmarked salary, annual target bonus, equity in an early-stage startup, and a comprehensive benefits plan, including 401(k) matching, a retirement safe harbor plan, and other perks.
At Metagenomi, we know that our people drive our success. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term career. We are an equal opportunity employer and believe in and value diversity and inclusion. All employment is decided on the basis of qualifications, merit, and business need.
If you need assistance or accommodation due to a disability, please contact us at hr@metagenomi.co and we would be happy to help!
Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi’s Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.