We are seeking an experienced Manufacturing Associate (Downstream) to support manufacturing operations at the pilot plant facility. Reporting to the Manufacturing Manager, this position will have the opportunity to build the pilot plant manufacturing operations, procedures, and tools from the ground up. This person will work cross-functionally with Process Engineering, Quality Assurance and Control, Facilities, and Logistics within the Technical Operations department. This is an on-site role based in Emeryville, California.
About the Role
By the end of your first 3 months, you will have a chance to demonstrate your ability to:
- Perform GMP manufacturing operations for downstream operations of recombinant protein production - filtration, TFF, chromatography, buffer preparation
- Perform basic troubleshooting and assist in the review of documentation for assigned functions
- Assist with or independently performs investigations for any operational and process deviations to implement the appropriate corrective actions.
- Participate on cross-functional teams and represent their functional area
- Draft and revise documents such as Manufacturing Procedures, SOPs, and technical reports
- Collaborate with other departments for raw materials, water, testing requirements, documentation, validation, maintenance, and scheduling
- Identify the technical, procedural, and equipment issues that hinder production and compliance and inform support departments and manager as needed
- Support the installation and qualification of new equipment
- Help create and actively support 5S, Area Improvement, and Safety Team initiatives to ensure a Continuous Improvement culture.
Desired Qualifications
- Undergraduate degree and at least three years of relevant industry experience
- Technical proficiency in GMP production
- Industry experience with filtration, chromatography and filling operations
- Experience with quality management systems and technical writing
- Experience with technology transfers and new process introductions
- Ability to troubleshoot issues, identify root causes and implement effective solutions
- Drive continuous process improvements in collaboration with the process engineering team
- Experience with the usage of quality management systems and technical writing
- Effective oral and written communication skills
- Extremely organized and able to efficiently manage your time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities
- Able to quickly learn and adapt to new software tools (Google Suite, Slack)
- Highly collaborative, team-oriented, and considerate of the needs of others. Thrives in a fast-moving, results-oriented startup environment with urgent deadlines
- Independent and self-sufficient, but knows when to ask questions or seek support
- Self-motivated, passionate about your work, and eager to continuously learn more experience with ordering consumables/supplies and tracking inventory.
The anticipated base salary range for this position will be $90,000 to $110,000 depending on the exact level of the role. As this role is open to candidates with a wide range of skills and experience, the actual salary will be dependent on the specific level of the position. We value transparency and will make every effort to provide you with a succinct explanation of how the final salary within this range is determined.
Please note, all candidates must be authorized to work in the United States.
About Metagenomi
Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world. For more information, please visit https://metagenomi.co/.
What makes Metagenomi a unique place to work?
- We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating disease.
- We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more!
- We offer competitive compensation including a market-benchmarked salary, annual target bonus, equity in an early-stage startup, and a comprehensive benefits plan, including 401(k) matching, a retirement safe harbor plan, and other perks.
At Metagenomi, we know that our people drive our success. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term career. We are an equal opportunity employer and believe in and value diversity and inclusion. All employment is decided on the basis of qualifications, merit, and business need.
If you need assistance or accommodation due to a disability, please contact us at hr@metagenomi.co and we would be happy to help!
Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi’s Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.