We are seeking a Senior Associate, Analytical Sciences and Quality Control to support assay development, qualification, and sample testing as a member of the Analytical Sciences and Quality Control team. Reporting to the Senior Scientist, this position contributes to analytical support to multiple programs in our portfolio. You will have the opportunity to make a lasting impact as you partner with Quality Control, Process Development, Manufacture and Preclinical teams. This role will be based in Emeryville, California.
How you’ll contribute:
- This position will play a supporting role, working within the analytical chemistry team on method development, transfer, qualification and validation and supporting material and lot release testing. This position is laboratory based and supports all drug modalities (both in vivo and ex vivo therapies) at Metagenomi
- Work with scientists on one or more projects to support identity, purity, impurity, potency, and other characterization testing
- Work on test method development, transfer, qualification and validation for in-process materials, lot release and stability, to support the Process Development and Manufacturing teams, execute in-house routine testing
- Follow SOPs or work instructions during assay execution; author summary reports
- Maintain accurate and complete documentation of any scientific experimental plan, data and report; operate under Good Documentation Practice for efficient data management and retrieval
- Ensure that all work follows the required regulatory standards, conforms to company policies and standard operating procedures (SOPs)
- Follow Environment, Health & Safety policies, ensure safe environmental and working conditions in the lab
- Work on multiple projects to meet departmental and organization goals
- Troubleshoot instruments and methods
What you bring:
- Undergraduate degree in Analytical chemistry, Biochemistry, Molecular biology, or other closely related chemistry or life sciences discipline, with at least five years of relevant experience in an analytical development lab and/or a QC analytical laboratory
- Hands-on experience in mRNA, LNP and protein analytical methods (e.g. HPLC (IPRP, SEC), CE, LCMS, residual solvent and impurities etc.), and molecular & biochemistry assays (e.g., qPCR, ELISA, wester blots, SDS-PAGE, etc.)
- Experience with gene and cell therapy, mRNA/LNP, CRISPR/Cas technology is an advantage
- Flexible to meet changing demands to support process development and manufacturing activities
- Ability to manage multiple tasks and meet deadlines with a high tolerance for ambiguity, solutions oriented and a ble to problem solve and identify root cause
- Strong interpersonal and communications skills; written and oral
- Highly collaborative, team-oriented
California Pay Transparency Disclosure:
This position is classified as an exempt position under the Federal Labor Standards Act. The anticipated base salary range for this position will be $100,000 -$115,000. You will also be eligible to receive equity, bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on location, skill level, years and depth of relevant experience, and education.
Please note, all candidates must be authorized to work in the United States.
About Metagenomi
Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world. For more information, please visit https://metagenomi.co/.
What makes Metagenomi a unique place to work?
- We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating disease.
- We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more!
- We offer competitive compensation including a market-benchmarked salary, annual target bonus, equity in an early-stage startup, and a comprehensive benefits plan, including 401(k) matching, a retirement safe harbor plan, and other perks.
At Metagenomi, we know that our people drive our success. We are an equal-opportunity employer and believe in and value diversity and inclusion. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. Metagenomi does not discriminate on the basis of race, color, religion, sexual orientation, gender, age, physical or mental disability, or any other status protected under federal, state, or local law. Please note, all candidates must be authorized to work in the United States.
Applicants/Employees have rights under various State and Federal Employment Laws, including
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Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi’s Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.