Senior Bioinformatics Engineer - Metagenomics

Metagenomi in Emeryville, California, United States

$150,000 - $170,000

We are seeking a motivated individual with a background in biology, metagenomics, and programming to support Metagenomi’s proprietary metagenomics-based discovery platform. Reporting to the metagenomics lead, this position will play a crucial role in designing methods to expand our metagenomics platform, including algorithm development, pipeline optimization, and big data analytics. This role will be based in Emeryville, California.

About the Role

  • Develop algorithms and computational infrastructure for processing, curating, and extracting value from metagenomic datasets
  • Automate methods for high throughput discovery of novel enzymes and systems from metagenomic data
  • Integrate diverse data sources for improved candidate protein discovery and predicted activity ranking
  • Apply software engineering best practices to optimize new and existing bioinformatics algorithms to run at scale and cost-effectively
  • Coordinate and encourage standardized coding best practices, lead and collaborate with team members on code reviews
  • Develop pipelines through their complete lifecycle, including testing, deployment, maintenance

Desired Qualifications

  • Ph.D. in Biology, Computer Science, Statistics, or closely related discipline or equivalent relevant experience working in biotechnology
  • Experience working with and optimizing common tools for metagenomics data analysis (assemblers, de novo protein prediction, functional annotation methods, hidden markov models, phylogenetic tree construction, protein clustering, gene neighborhood analysis)
  • Extensive knowledge of NGS platforms, including their mechanisms and technical limitations
  • Demonstrated skill in pipeline development, preferably using Nextflow
  • Experience with full lifecycle development of software and pipelines
  • Advanced proficiency in Python and experience or a strong interest in working with cloud computing systems
  • Experience with Docker and building containerized data workflows to handle large scale data streams
  • Familiarity with software development practices such as unit testing, code reviews, and version control.

The anticipated base salary range for this position will be $150,000 to $170,000, depending on the exact level of the role. As this role is open to candidates with a wide range of skills and experience, the actual salary will be dependent on the specific level of the position. We value transparency and will make every effort to provide you with a succinct explanation for how the final salary within this range is determined.

Please note, all candidates must be authorized to work in the United States.

About Metagenomi

Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world. For more information, please visit https://metagenomi.co/.

What makes Metagenomi a unique place to work?

  • We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating disease.
  • We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more!
  • We offer competitive compensation including a market-benchmarked salary, annual target bonus, equity in an early-stage startup, and a comprehensive benefits plan, including 401(k) matching, a retirement safe harbor plan, and other perks.

At Metagenomi, we know that our people drive our success. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term career. We are an equal opportunity employer and believe in and value diversity and inclusion. All employment is decided on the basis of qualifications, merit, and business need.

If you need assistance or accommodation due to a disability, please contact us at hr@metagenomi.co and we would be happy to help!

Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi’s Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.

Apply